Bcl9 - B cell CLL/lymphoma 9 Gene

Also Known as Gm130; 2610202E01Rik; 8030475K17Rik; A330041G23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 77578

Summary

Enables beta-catenin binding activity. Acts upstream of or within several processes, including myotube differentiation involved in skeletal muscle regeneration; skeletal muscle cell differentiation; and somatic stem cell population maintenance. Located in cis-Golgi network and nucleus. Is expressed in several structures, including brain; eye; head surface ectoderm; metanephros; and thymus primordium. Orthologous to human BCL9 (BCL9 transcription coactivator). [provided by Alliance of Genome Resources, Apr 2022]

Bcl9 Products (1)

mRNA Protein Name
NM_029933.4 NP_084209.3 B-cell CLL/lymphoma 9 protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables beta-catenin binding IPI
IPI: Inferred from physical interaction
15574752 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within canonical Wnt signaling pathway IGI
IGI: Inferred from genetic interaction
19699733 MGI
acts upstream of or within myoblast differentiation IGI
IGI: Inferred from genetic interaction
19699733 MGI
acts upstream of or within myotube differentiation involved in skeletal muscle regeneration IGI
IGI: Inferred from genetic interaction
19699733 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
15574752 MGI
acts upstream of or within skeletal muscle cell differentiation IGI
IGI: Inferred from genetic interaction
19699733 MGI
acts upstream of or within somatic stem cell population maintenance IGI
IGI: Inferred from genetic interaction
20682801 MGI
acts upstream of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
19699733 MGI
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
20691678 MGI
located in cis-Golgi network IDA
IDA: Inferred from direct assay
24239381 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
15574752 MGI
located in nucleus IDA
IDA: Inferred from direct assay
15574752 MGI
located in sarcoplasm IDA
IDA: Inferred from direct assay
19699733 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

B-cell CLL/lymphoma 9 protein

  • B-cell lymphoma 9 protein

  • bcl-9

  • nuclear co-factor of beta-catenin signalling

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (13)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-132300 ZW4864 Inhibitor 98.06% Unkown
HY-132300A ZW4864 free base Inhibitor 99.42% Unkown
HY-163768 Antitumor agent-172 Inhibitor 98.51% Unkown
HY-163767 Antitumor agent-171 Inhibitor 98.48% Unkown
HY-148918 E722-2648 Inhibitor / Unkown
HY-148918A E722-2648 TFA Inhibitor 96.33% Unkown
HY-161087 β-catenin/BCL9 PPI-IN-1 Inhibitor / Unkown
HY-RS01443 BCL9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01444 BCL9L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21497 Bcl9l Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22110 Bcl9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28015 Bcl9l Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28632 Bcl9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bcl9 NCBI NCBI:607