Fabp3 - fatty acid binding protein 3 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 79131

Summary

Enables icosatetraenoic acid binding activity and long-chain fatty acid transporter activity. Involved in several processes, including long-chain fatty acid transport; response to fatty acid; and response to Insulin. Located in cytosol and sarcoplasm. Human ortholog(s) of this gene implicated in hypertension and type 2 diabetes mellitus. Orthologous to human FABP3 (fatty acid binding protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Fabp3 Products (1)

mRNA Protein Name
NM_024162.2 NP_077076.1 fatty acid-binding protein, heart

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables fatty acid binding IPI
IPI: Inferred from physical interaction
7929039 RGD
enables icosatetraenoic acid binding IPI
IPI: Inferred from physical interaction
11170430 RGD
enables long-chain fatty acid transmembrane transporter activity IPI
IPI: Inferred from physical interaction
8573586 RGD
Biological Process GO Annotation Evidence References Source
involved in fatty acid metabolic process IEP
IEP: Inferred from expression pattern
3036869 RGD
involved in long-chain fatty acid transport IDA
IDA: Inferred from direct assay
8573586 RGD
involved in response to fatty acid IEP
IEP: Inferred from expression pattern
17001452 RGD
involved in response to insulin IEP
IEP: Inferred from expression pattern
7744030 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
15491498 RGD
Cellular Component GO Annotation Evidence References Source
located in sarcoplasm IDA
IDA: Inferred from direct assay
2032944 RGD
NOT located in sarcoplasmic reticulum IDA
IDA: Inferred from direct assay
2032944 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fatty acid-binding protein, heart

  • Fatty acid binding protein 3 heart

  • H-FABP

  • fatty acid binding protein 3, muscle and heart

  • heart fatty acid binding protein

  • heart-type fatty acid-binding protein

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-P4115 CooP / Phase 2

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-101903 BMS-309403 Inhibitor 99.91% Unkown
HY-101903A BMS-309403 sodium Inhibitor 99.89% Unkown
HY-161702 RO6806051 Inhibitor 99.82% Unkown
HY-163032 FABP4-IN-3 Inhibitor 99.64% Unkown
HY-W040255 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine 99.9% Unkown
HY-148665 FABP-IN-2 Inhibitor 99.78% Unkown
HY-149953 FABP4-IN-2 Inhibitor / Unkown
HY-178471 FABP4/5-IN-6 Inhibitor / Unkown
HY-RS04659 FABP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16971 Fabp3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23414 Fabp3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fabp3 NCBI NCBI:2170