Hmox2 - heme oxygenase 2 Gene

Also Known as Ho-2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 79239

Summary

Enables heme oxygenase (decyclizing) activity. Involved in response to oxidative stress. Predicted to be located in plasma membrane. Orthologous to human HMOX2 (heme oxygenase 2). [provided by Alliance of Genome Resources, Apr 2022]

Hmox2 Products (2)

mRNA Protein Name
NM_001277073.1 NP_001264002.1 heme oxygenase 2
NM_024387.2 NP_077363.1 heme oxygenase 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables heme oxygenase (decyclizing) activity IDA
IDA: Inferred from direct assay
1575508 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
15175337 RGD
Biological Process GO Annotation Evidence References Source
involved in response to oxidative stress IDA
IDA: Inferred from direct assay
11950143 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

heme oxygenase 2

  • heme oxygenase (decycling) 2

Hmox2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Hmox2 P23711 Calm1 Rattus norvegicus P0DP29
Anti Bait CoIP
15175337
Intra
Hmox2 P23711 Calm1 Rattus norvegicus P0DP29
Y2H
15175337
Cross
Hmox2 P23711 CALM Bos taurus P62157
Pull Down
15175337
Cross
Hmox2 P23711 CALM Bos taurus P62157
Enzymatic Study
15175337
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-146577 Keap1-Nrf2-IN-7 Inhibitor 99.82% Unkown
HY-146578 Keap1-Nrf2-IN-8 Inhibitor / Unkown
HY-RS06250 HMOX2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-162096 Keap1-Nrf2-IN-17 Inhibitor / Unkown
HY-RS17550 Hmox2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24009 Hmox2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hmox2 NCBI NCBI:3163