VCPIP1 - valosin containing protein interacting protein 1 Gene

Homo sapiens

Also known as DUBA3; VCIP135

Gene ID: 80124 | Gene type: protein coding

About VCPIP1

Cytogenetic location: 8q13.1 Genomic coordinates (GRCh38): 8:66,628,487-66,667,231 (from NCBI)

This gene has 1 transcript (splice variant) and 209 orthologues. Ubiquitous expression in bone marrow (RPKM 10.6), spleen (RPKM 6.5) and 25 other tissues.

Summary

Enables thiol-dependent Deubiquitinase. Involved in protein deubiquitination; protein-DNA covalent cross-linking repair; and regulation of protein localization to chromatin. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

VCPIP1 Products(1)

mRNA	Protein	Name
NM_025054.5	NP_079330.2	deubiquitinating protein VCPIP1

VCPIP1 Protein Structure

OTU

0
200
400
600
800
1000
1222 a.a.

Protein Preferred Names

Protein Names

deubiquitinating protein VCPIP1

VCP/p47 complex-interacting 135-kDa protein

Related Diseases

Diseases

Alias

Inclusion Body Myopathy With Paget Disease Of Bone And Frontotemporal Dementia

Ibmpfd	Inclusion Body Myopathy With Early-Onset Paget Disease And Frontotemporal Dementia
Pagetoid Amyotrophic Lateral Sclerosis	Pagetoid Neuroskeletal Syndrome
Inclusion Body Myopathy With Paget Disease Of Bone And/Or Frontotemporal Dementia	Inclusion Body Myopathy With Early-Onset Paget Disease Of Bone And/Or Frontotemporal Dementia
Multisystem Proteinopathy	Limb-Girdle Muscular Dystrophy With Paget Disease Of Bone
Inclusion Body Myopathy With Paget'S Disease Of Bone And Frontotemporal Dementia	Inclusion Body Myopathy With Early-Onset Paget Disease And Frontotemporal Dement
Lower Motor Neuron Degeneration With Paget-Like Bone Disease	Muscular Dystrophy, Limb-Girdle, With Paget Disease Of Bone
Myopathy, Inclusion Body, With Early-Onset Paget Disease And Frontotemporal Dementia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15624	VCPIP1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	VCPIP1	VGNC	VGNC:48244
Rattus norvegicus	VCPIP1	RGD	RGD:708520
Felis catus	VCPIP1	VGNC	VGNC:66934
Macaca mulatta	VCPIP1	VGNC	VGNC:79895
Mus musculus	VCPIP1	MGD	MGI:1917925
Others	VCPIP1	NCBI

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