MFAP5 - microfibril associated protein 5 Gene

Also Known as AAT9; MP25; MAGP2; MAGP-2; MFAP-5

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 8076

About MFAP5

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:8,645,943-8,662,826 (from NCBI)

This gene has 15 transcripts (splice variants), 185 orthologues, 1 paralogue and is associated with 2 phenotypes. Biased expression in fat (RPKM 53.2), endometrium (RPKM 51.6) and 11 other tissues.

Summary

This gene encodes a 25-kD microfibril-associated glycoprotein which is a component of microfibrils of the extracellular matrix. The encoded protein promotes attachment of cells to microfibrils via alpha-V-beta-3 Integrin. Deficiency of this gene in mice results in neutropenia. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

MFAP5 Products (5)

mRNA Protein Name
NM_001297709.2 NP_001284638.1 microfibrillar-associated protein 5 isoform b precursor
NM_001297710.2 NP_001284639.1 microfibrillar-associated protein 5 isoform c precursor
NM_001297711.2 NP_001284640.1 microfibrillar-associated protein 5 isoform d precursor
NM_001297712.2 NP_001284641.1 microfibrillar-associated protein 5 isoform e precursor
NM_003480.4 NP_003471.1 microfibrillar-associated protein 5 isoform a precursor

MFAP5 Protein Structure

MAGP

MAGP: Microfibril-associated glycoprotein (MAGP) (3 - 138)

  • 0
  • 100
  • 173 a.a.
Protein Preferred Names Protein Names

microfibrillar-associated protein 5

  • THE1A-MFAP5

Recombinant MFAP5 Proteins

Cat. No. Product Name Accession Purity
HY-P76494 MAGP-2/MFAP5 Protein, Human (HEK293, His) Q13361-1 (I22-L173) ≥ 85%, as determined by reducing SDS-PAGE.

MFAP5 Antibodies

Cat. No. Product Name Application Reactivity
HY-P81372 MAGP2 Antibody (YA1117) IHC-P Human
HY-P81372A MAGP2 Antibody (YA1117)(PBS only) IHC-P Human

Related Diseases

Diseases Alias
Aortic Aneurysm, Familial Thoracic 9

  • AAT9

  • Aortic Aneurysm, Thoracic, With Or Without Aortic Dissection

  • Aneurysm, Aortic, Thoracic, Familial, Type 9
Aortic Aneurysm, Familial Thoracic 1

  • Thoracic Aortic Aneurysm

  • Annuloaortic Ectasia

  • Familial Thoracic Aortic Aneurysm And Aortic Dissection

  • Familial Aortic Dissection

  • Familial Taad

  • Familial Thoracic Aortic Aneurysm

  • Congenital Aneurysm Of Ascending Aorta

  • Familial Aortic Aneurysm

  • Familial Thoracic Aortic Aneurysm And Dissection

  • Aortic Aneurysm, Thoracic

  • AAT1

  • Faa1

  • Aortic Dissection, Familial

  • Aortic Aneurysm, Familial Thoracic

  • Aneurysm, Thoracic Aortic

  • Faa

  • Ftaad

  • Taa

  • Taad

  • Cystic Medial Necrosis Of Aorta

  • Familial Non-Syndromic Thoracic Aortic Aneurysm And Aortic Dissection

  • Aortic Aneurysm Thoracic

  • Familial Aortic Aneurysms

  • Aneurysm, Aortic, Thoracic, Familial, Type 1

  • Aneurysm Of Thoracic Aorta

  • Intrathoracic Aneurysm

  • Thoracic Aorta Aneurysm

  • Thoracic Aortic Aneurysm Without Rupture

  • Thoracic Aneurysm

  • Thorax Arterial Aneurysm

  • Thoracic Artery Aneurysm

  • Thoracic Arterial Aneurysm

  • Thorax Aneurysm

  • Thorax Aortic Aneurysm

  • Dissection Of Thoracic Aorta
Aortic Aneurysm

  • Aortic Rupture

  • Thoracoabdominal Aortic Aneurysm, Ruptured

  • Ruptured Aortic Aneurysm

  • Aortic Aneurysms

  • Aortic Aneurysm Without Mention Of Rupture Nos

  • Ruptured Abdominal Aortic Aneurysm

  • Aortic Aneurysm, Ruptured

  • Ruptured Thoracic Aortic Aneurysm
Contractural Arachnodactyly, Congenital

  • Congenital Contractural Arachnodactyly

  • Beals Syndrome

  • CCA

  • Beals-Hecht Syndrome

  • Distal Arthrogryposis Type 9

  • Arthrogryposis, Distal, Type 9

  • Da9

  • Arachnodactyly, Contractural Beals Type

  • Contractures, Multiple With Arachnodactyly

  • Ear Anomalies-Contractures-Dysplasia Of Bone With Kyphoscoliosis

  • Arthrogyroposis, Distal, Type 9

  • Distal Arthrogyropsis Type 9

  • Cca Syndrome

  • Arachnodactyly
Loeys-Dietz Syndrome

  • Loeys-Dietz Aortic Aneurysm Syndrome

  • Lds

  • Aortic Aneurysm Syndrome Due To Tgf-Beta Receptors Anomalies

  • Furlong Syndrome
Ovarian Cancer

  • Ovarian Carcinoma

  • Ovarian Neoplasm

  • Malignant Tumour Of Ovary

  • Cancer Of The Ovary

  • Epithelial Ovarian Cancer

  • Neoplasm Of Ovary

  • Ovarian Neoplasms

  • Ovarian Cancers

  • Malignant Neoplasm Of Ovary

  • Primary Malignant Neoplasm Of Ovary

  • Ovarian Cancer, Somatic

  • Malignant Ovarian Tumor

  • Ovary Neoplasm

  • Primary Ovarian Cancer

  • Tumor Of The Ovary

  • Malignant Neoplasm Of The Ovary

  • Malignant Tumor Of The Ovary

  • Ovarian Malignant Tumor

  • OC

  • Ovarian Carcinomas

  • Cancer, Ovarian

  • Cancer Of Ovary

  • Ovary Cancer

  • Ca Ovary
Aortic Dissection
Ehlers-Danlos Syndrome

  • Eds

  • Cutis Hyperelastica

  • Elastic Skin

  • Ehlers-Danlos Syndromes

  • Ed Syndrome

  • Ehlers Danlos Syndrome

  • Ehlers Danlos Disease

  • Eds - [Ehlers-Danlos Syndrome]
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08379 MFAP5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16286 Mfap5 Mouse Pre-designed siRNA Set A / Unkown
HY-RS24877 Mfap5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus MFAP5 VGNC VGNC:31425
Canis familiaris MFAP5 VGNC VGNC:43191
Mus musculus MFAP5 MGD MGI:1354387
Macaca mulatta MFAP5 VGNC VGNC:74621
Rattus norvegicus MFAP5 RGD RGD:1307919
Others MFAP5 NCBI