Ctbp2 - C-terminal binding protein 2 Gene

Predicted to enable several functions, including identical protein binding activity; retinoic acid receptor binding activity; and transcription corepressor binding activity. Predicted to be a structural constituent of presynaptic active zone. Predicted to be involved in negative regulation of transcription, DNA-templated; synaptic vesicle docking; and white fat cell differentiation. Predicted to act upstream of or within several processes, including cellular response to leukemia inhibitory factor; positive regulation of chromatin binding activity; and positive regulation of retinoic acid receptor signaling pathway. Predicted to be located in several cellular components, including GABA-ergic synapse; glutamatergic synapse; and ribbon synapse. Predicted to be part of transcription repressor complex. Predicted to be active in photoreceptor ribbon synapse; presynaptic active zone cytoplasmic component; and presynaptic cytosol. Orthologous to human CTBP2 (C-terminal binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]