EFCAB2 - EF-hand calcium binding domain 2 Gene

Also Known as DRC8; CFAP200

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 84288

About EFCAB2

Cytogenetic location: 1q44 Genomic coordinates (GRCh38): 1:244,969,682-245,125,229 (from NCBI)

This gene has 16 transcripts (splice variants), 161 orthologues and 20 paralogues. Ubiquitous expression in thyroid (RPKM 1.2), testis (RPKM 1.2) and 25 other tissues.

Summary

The gene encodes a protein that contains two EF-hand calcium-binding domains although its function has yet to be determined. Alternatively spliced transcripts have been observed. [provided by RefSeq, Mar 2014]

EFCAB2 Products (3)

mRNA	Protein	Name
NM_001143943.1	NP_001137415.1	dynein regulatory complex protein 8 isoform b
NM_001290327.2	NP_001277256.1	dynein regulatory complex protein 8 isoform c
NM_032328.4	NP_115704.1	dynein regulatory complex protein 8 isoform a

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

EFCAB2 Protein Structure

EF-hand_6

0
100
200
269 a.a.

Protein Preferred Names	Protein Names
dynein regulatory complex protein 8	EF-hand calcium-binding domain-containing protein 2

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04184	EFCAB2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	EFCAB2	VGNC	VGNC:72128
Mus musculus	EFCAB2	MGD	MGI:1915476
Rattus norvegicus	EFCAB2	RGD	RGD:1308593
Bos taurus	EFCAB2	VGNC	VGNC:28343
Canis familiaris	EFCAB2	VGNC	VGNC:106598
Felis catus	EFCAB2	VGNC	VGNC:61739
Others	EFCAB2	NCBI