RNGTT - RNA guanylyltransferase and 5'-phosphatase Gene

Homo sapiens

Also known as HCE; HCE1; hCAP; CAP1A

Gene ID: 8732 | Gene type: protein coding

About RNGTT

Cytogenetic location: 6q15 Genomic coordinates (GRCh38): 6:88,609,897-88,963,618 (from NCBI)

This gene has 4 transcripts (splice variants), 207 orthologues and 1 paralogue. Ubiquitous expression in lymph node (RPKM 8.1), testis (RPKM 5.3) and 24 other tissues.

Summary

Enables mRNA guanylyltransferase activity and triphosphatase activity. Involved in 7-methylguanosine mRNA capping. Predicted to be located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RNGTT Products(3)

mRNA	Protein	Name
NM_001286426.2	NP_001273355.1	mRNA-capping enzyme isoform b
NM_001286428.2	NP_001273357.1	mRNA-capping enzyme isoform c
NM_003800.5	NP_003791.3	mRNA-capping enzyme isoform a

RNGTT Protein Structure

DSPc

mRNA_cap_enzyme

mRNA_cap_C

0
100
200
300
400
500
597 a.a.

Protein Preferred Names

Protein Names

mRNA-capping enzyme

HCAP1

Related Diseases

Diseases

Alias

Cecum Carcinoma

Cecum Cancer	Caecum Carcinoma
Carcinoma Of Cecum	Cecal Cancer
Malignant Neoplasm Of Caecum	Malignant Tumor Of The Cecum

Cecum Adenocarcinoma

Cecal Adenocarcinoma

Adenocarcinoma Of Cecum

Photokeratitis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12099	RNGTT Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	RNGTT	VGNC	VGNC:76709
Felis catus	RNGTT	VGNC	VGNC:102508
Rattus norvegicus	RNGTT	RGD	RGD:1311410
Bos taurus	RNGTT	VGNC	VGNC:34076
Canis familiaris	RNGTT	VGNC	VGNC:45679
Mus musculus	RNGTT	MGD	MGI:1329041

Name
Email *

	Sorry, but the email address you supplied was invalid.