BPY2 - basic charge Y-linked 2 Gene

Also Known as VCY2; BPY2A; VCY2A

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9083

About BPY2

Cytogenetic location: Yq11.223 Genomic coordinates (GRCh38): Y:22,984,263-23,005,465 (from NCBI)

This gene has 4 transcripts (splice variants), 4 orthologues, 2 paralogues and is associated with 1 phenotype.

Summary

This gene is located in the nonrecombining portion of the Y chromosome, and expressed specifically in testis. The encoded protein interacts with ubiquitin protein Ligase E3A and may be involved in male germ cell development and male infertility. Three nearly identical copies of this gene exist on chromosome Y; two copies are part of a palindromic region. This record represents the copy outside of the palidromic region. [provided by RefSeq, Jul 2008]

BPY2 Products (1)

mRNA Protein Name
NM_004678.3 NP_004669.2 testis-specific basic protein Y 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables HECT domain binding IPI
IPI: Inferred from physical interaction
12207887 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
14627543 GOA
Biological Process GO Annotation Evidence References Source
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
12724276 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
12724276 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

testis-specific basic protein Y 2

  • basic protein on Y chromosome 2

Related Diseases

Diseases Alias
Spermatogenic Failure, Y-Linked, 2

  • SPGFY2

  • Spermatogenic Failure, Nonobstructive, Y-Linked

  • Y-Linked Spermatogenic Failure 2

  • Azoospermia, Nonobstructive, Y-Linked

  • Oligozoospermia, Nonobstructive, Y-Linked

  • Oligospermia, Nonobstructive, Y-Linked

  • Spermatogenic Arrest, Y-Linked

  • Nonobstructive Y-Linked Spermatogenic Failure

  • Spermatogenic Failure Y-Linked 2

  • Azoospermia Non-Obstructive Y-Linked

  • Non-Obstructive Azoospermia And Infertility

  • Oligospermia Non-Obstructive Y-Linked

  • Oligozoospermia Non-Obstructive Y-Linked

  • Spermatogenic Arrest Y-Linked

  • Spermatogenic Failure Nonobstructive Y-Linked
Male Infertility

  • Infertility, Male

  • Infertility Male

  • Male Sterility

  • Absolute Infertility
Infertility
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W004547 (NH2)2bpy 99.91% Unkown
HY-W127716 Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 97.78% Unkown
HY-D0148 Ru(bpy)2(phen-ITC)(PF6)2 / Unkown
HY-RS01587 BPY2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown