Trim33 - tripartite motif-containing 33 Gene
Also Known as Ecto; Tif1g; 8030451N04Rik
Species: Mus musculus
Summary
Predicted to enable R-SMAD binding activity and co-SMAD binding activity. Predicted to be involved in negative regulation of BMP signaling pathway; protein ubiquitination; and regulation of transforming growth factor beta receptor signaling pathway. Located in nucleus. Is expressed in genitourinary system and submandibular gland primordium. Orthologous to human TRIM33 (tripartite motif containing 33). [provided by Alliance of Genome Resources, Apr 2022]
Trim33 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001079830.2 | NP_001073299.1 | E3 ubiquitin-protein ligase TRIM33 isoform 2 |
| NM_053170.3 | NP_444400.2 | E3 ubiquitin-protein ligase TRIM33 isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables promoter-specific chromatin binding |
IDA
IDA: Inferred from direct assay
|
26624618 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
21531907 | MGI |
| enables ubiquitin protein ligase activity |
IDA
IDA: Inferred from direct assay
|
26624618 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in gene expression |
IMP
IMP: Inferred from mutant phenotype
|
26624618 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
15314655 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
E3 ubiquitin-protein ligase TRIM33 |
|
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