GlcB-IN-1
GlcB-IN-1 is an inhibitor of Mycobacterium malate synthase (GlcB) with an IC50 of 1.05 μM. GlcB-IN-1 can be used for the research of tuberculosis.
For research use only. We do not sell to patients.
- CAS No.: 1346745-52-5
- Formula: C12H9NO4
- Molecular Weight:231.20
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
GlcB-IN-1 (compound 19) binds to malate synthase (GlcB) from Mycobacterium tuberculosis, and the resulting complex retains the closed active site lid and the "inward" conformation of the CoA-binding loop, forming a weak hydrogen bond with Met-631[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1346745-52-5
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Molecular Weight 231.20
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Formula C12H9NO4
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SMILES
O=C(/C=C(C(O)=O)\O)C1=CNC2=CC=CC=C21
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)