Glutaminase C-IN-2
Glutaminase C-IN-2 (compound 11) is glutaminase C (GAC) allosteric inhibitor with an IC50 of 10.64 nM. Glutaminase C-IN-2 regulates the cellular metabolite, thereby increasing reactive oxygen species (ROS) by blocking glutamine metabolism. Glutaminase C-IN-2 has anticancer effects.
For research use only. We do not sell to patients.
- CAS No.: 3056437-77-2
- Formula: C24H23N7O2S
- Molecular Weight:473.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
4.042 nM
Compound: 11
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Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-glo assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-glo assay
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[PMID: 37849538] |
Chemical Information
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CAS No. 3056437-77-2
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Molecular Weight 473.55
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Formula C24H23N7O2S
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SMILES
O=C(NC1=NN=C(N[C@H]2CN(C3=NN=CC=C3)CC2)S1)CC4=CC=CC(OC5=CC=CC=C5)=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Glutaminase C-IN-2 Related Classifications
HY-149602 Related Classifications
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