3056437-77-2
3056437-77-2
Chemical Structure
Glutaminase C-IN-2
- CAS No.: 3056437-77-2
- Formula:C24H23N7O2S
- Molecular Weight:473.55
InChIKey: JOKJBMFEUFULOX-GOSISDBHSA-N
SMILES: O=C(NC1=NN=C(N[C@H]2CN(C3=NN=CC=C3)CC2)S1)CC4=CC=CC(OC5=CC=CC=C5)=C4
Biological Activity: Glutaminase C-IN-2 (compound 11) is glutaminase C (GAC) allosteric inhibitor with an IC50 of 10.64 nM. Glutaminase C-IN-2 regulates the cellular metabolite, thereby increasing reactive oxygen species (ROS) by blocking glutamine metabolism. Glutaminase C-IN-2 has anticancer effects[1].
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Glutaminase C-IN-2 | Glutaminase C-IN-2 (compound 11) is glutaminase C (GAC) allosteric inhibitor with an IC50 of 10.64 nM. Glutaminase C-IN-2 regulates the cellular metabolite, thereby increasing reactive oxygen species (ROS) by blocking glutamine metabolism. Glutaminase C-IN-2 has anticancer effects. | |||||||||||||||||||||
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References
Keywords
