Glutathione maleimide
Glutathione maleimide (GS-Mal) is a glutathione depletor and oxidative stress inducer that reduces intracellular GSH levels in cancer cells and induces apoptosis. Glutathione maleimide can selectively extract and quantify GSH from complex biological samples, and the polymeric micelles prepared from it also inhibit the growth of cancer cells in a concentration-dependent manner. Glutathione maleimide has broad applications in breast cancer and related fields.
For research use only. We do not sell to patients.
- CAS No.: 137593-43-2
- Formula: C14H17N3O8S
- Molecular Weight:387.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 137593-43-2
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Molecular Weight 387.37
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Formula C14H17N3O8S
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SMILES
OC(CNC([C@H](CS)NC(CC[C@H](N1C(C=CC1=O)=O)C(O)=O)=O)=O)=O
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Synonyms
GS-Mal
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Oh H, Lee J, Yeo W S. Selective Extraction and Quantification of Glutathione using Maleimide-Presenting Gold Nanoparticles[J]. Bulletin of the Korean Chemical Society, 2014, 35(10): 3047. [Content Brief]
[2]. Babanyinah GK, et al.. Maleimide functionalized polycaprolactone micelles for glutathione quenching and doxorubicin delivery. Chemical science. 2024 Jul 03;15(26):9987-10001. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Glutathione maleimide Related Classifications
HY-183401 Related Classifications
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