Glutathione Reductase, baker's yeast
Based on 1 Customer Validation
Glutathione reductase, baker's yeast (EC 1.6.4.2) is a reductase. Glutathione reductase, baker's yeast eliminates intracellular ROS. Glutathione reductase, baker's yeast reduces oxidized glutathione (GSSG) to reduced glutathione (GSH) using NADPH as an electron donor. Glutathione reductase, baker's yeast exerts antioxidant activity. Glutathione reductase is mainly used to study diseases associated with oxidative stress, such as Parkinson's disease and sickle cell anemia.
For research use only. We do not sell to patients.
- CAS No.: 9001-48-3
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
Product Information
Molecular weight: 124 kDa
Inhibitors: N-alkylmaleimide, benzyl selensulfate, 2-chloroethyl isocyanate, Cu2+, 2,4-dihydroxybenzylamine, 1-fluoro-2,4-dinitrobenzene, p-nitrobenzyl selensulfate, 2-triazine-5-nitrofuran
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
EC Number
1.6.4.2
Specific Activity
100-300 U/mg protein
Unit Definition
One unit is defined as the amount of enzyme that will reduce 1.0 μmoL of Oxidized Glutathione per min at pH 7.6 at 25°C.
Chemical Information
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CAS No. 9001-48-3
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Appearance Liquid
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Color Colorless to light yellow
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SMILES
[Glutathione Reductase, baker's yeast]
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Synonyms
EC 1.6.4.2; GR
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (265 KB)
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SDS (418 KB)
- English - EN (418 KB)
- Français - FR (418 KB)
- Deutsch - DE (418 KB)
- Norwegian - NO (418 KB)
- Español - ES (418 KB)
- Swedish - SV (418 KB)
- Italian - IT (418 KB)
- Korean - KR (418 KB)
- Portuguese - PT (418 KB)
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Handling Instructions (2659 KB)
References
[1]. Couto N, et al. The role of glutathione reductase and related enzymes on cellular redox homoeostasis network. Free Radic Biol Med. 2016 Jun;95:27-42. [Content Brief]
[2]. ASUQUO E B. INHIBITORY EFFECT OF FLUOXETINE ON GLUTATHIONE REDUCTASE PURIFIED FROM BAKER’S YEAST.
[3]. Dalmizrak O, et al. Mechanistic and structural insights into the in vitro inhibitory action of hypericin on glutathione reductase purified from baker's yeast. J Biochem Mol Toxicol. 2018 May;32(5):e22051. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)