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    Stem Cell/Wnt
  2. GSK-3
  3. GSK-3β inhibitor 1

GSK-3β inhibitor 1 

Cat. No.: HY-126144
Handling Instructions

GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM.

For research use only. We do not sell to patients.

GSK-3β inhibitor 1 Chemical Structure

GSK-3β inhibitor 1 Chemical Structure

CAS No. : 187325-53-7

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Top Publications Citing Use of Products

Publications Citing Use of MCE GSK-3β inhibitor 1

    GSK-3β inhibitor 1 purchased from MCE. Usage Cited in: Drug Des Devel Ther. 2019 Jun 24;13:2057-2066. 

    MLTC-1 cells are treated with Rg3 (0, 10, 20 μM) or Rg3 (20 μM) plus GSK3β inhibitor 1 (20 nM) for 24 hrs. Expression level of GSK3β in MLTC-1 cells is detected with Western blotting. The relative expression of GSK3β is quantified via normalization to β-actin.

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    Description

    GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM[1].

    IC50 & Target[1]

    GSK-3β

    4.9 nM (IC50)

    Molecular Weight

    222.24

    Formula

    C₁₄H₁₀N₂O

    CAS No.

    187325-53-7

    SMILES

    O=C1NC2=CC=CC=C2/C1=C/C3=NC=CC=C3

    Shipping

    Room temperature in continental US; may vary elsewhere

    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.

    References
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    GSK-3β inhibitor 1
    Cat. No.:
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