pCXCL8-1aa
Based on 1 Customer Validation
pCXCL8-1aa is an anti-inflammatory peptide. pCXCL8-1aa competitively inhibits the binding of CXCL8 to glycosaminoglycans such as heparin sulfate (HS) by binding with high affinity. This reduces the presentation of CXCL8 on the surface of vascular endothelial cells, thereby inhibiting neutrophil migration and inflammatory responses. pCXCL8-1aa can be used to study inflammatory diseases such as rheumatoid arthritis.
For research use only. We do not sell to patients.
- Purity: 98.13%
- Formula: C55H91N17O17
- Molecular Weight:1262.41
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 1262.41
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Formula C55H91N17O17
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Color White to off-white
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Sequence
Ac-Glu-Lys-Phe-Leu-Lys-Arg-Ala-Glu-Asn-Ser-NH2
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Sequence Shortening
Ac-EKFLKRAENS-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (79.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7921 mL | 3.9607 mL | 7.9214 mL | 19.8034 mL |
| 5 mM | 0.1584 mL | 0.7921 mL | 1.5843 mL | 3.9607 mL | |
| 10 mM | 0.0792 mL | 0.3961 mL | 0.7921 mL | 1.9803 mL | |
| 15 mM | 0.0528 mL | 0.2640 mL | 0.5281 mL | 1.3202 mL | |
| 20 mM | 0.0396 mL | 0.1980 mL | 0.3961 mL | 0.9902 mL | |
| 25 mM | 0.0317 mL | 0.1584 mL | 0.3169 mL | 0.7921 mL | |
| 30 mM | 0.0264 mL | 0.1320 mL | 0.2640 mL | 0.6601 mL | |
| 40 mM | 0.0198 mL | 0.0990 mL | 0.1980 mL | 0.4951 mL | |
| 50 mM | 0.0158 mL | 0.0792 mL | 0.1584 mL | 0.3961 mL | |
| 60 mM | 0.0132 mL | 0.0660 mL | 0.1320 mL | 0.3301 mL |
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