Hapten
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Hapten (165)
- Formula: C12H11NO4S
- Molecular Weight: 265.29
3-(((1,3-Dioxoisoindolin-2-yl)methyl)thio)propanoic acid (MFP) is a hapten with a carboxyl group at the end of its spacer arm, suitable for reacting with free amine groups of proteins. 3-(((1,3-Dioxoisoindolin-2-yl)methyl)thio)propanoic acid can be combined with carrier proteins and used in antigen design.
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- Formula: C57H86N20O14S2
- Molecular Weight: 1339.55
IMP 243 is a symmetric di-HSG (histamine-succinyl-glycine) bivalent hapten containing a Tscg-Cys ligand and two HSG groups. IMP 243 can be radiolabeled with 99mTc-pertechnetate. IMP 243 can be conjugated to other peptides to design bispecific antibodies (bsMAbs) for cancer research.
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- Formula: C18H30N2O2S
- Molecular Weight: 338.51
HSMO9 is a (+)-methamphetamine (METH)-like hapten that can be coupled to a carrier protein. HSMO9 can be used in vaccine development.
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- Formula: C24H22F5N3O3
- Molecular Weight: 495.44
FXb is an immunizing and functionalized hapten and can be used for protein bioconjugates preparation.
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- Formula: C32H36N4O2
- Molecular Weight: 508.65
Methylpyrroporphyrin XXI acid is a hapten that can be coupled with bovine serum albumin and keyhole limpet hemocyanin. Methylpyrroporphyrin XXI acid can target porphyrin with IC50 of 1.3 μM.
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- Formula: C47H75N11O18
- Molecular Weight: 1082.16
DOTA-Tyr-Lys-DOTA is a DOTA-based small molecule hapten. DOTA-Tyr-Lys-DOTAexhibits rapid clearance and low whole-body retention. DOTA-Tyr-Lys-DOTA can used in study pretargeted radioimmunotherapy.
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- Formula: C34H36N6O9
- Molecular Weight: 672.68
DNP-PEG2-NHCO-C2-DBCO is a clickable hapten that bears a dinitrophenyl (DNP) moiety as the antibody‐recruiting motif at one end, a polyethylene glycol chain as a spacer and a dibenzocyclooctene at the other end for the SPAAC chemistry.
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- Formula: C13H15Cl2NO4
- Molecular Weight: 320.17
Dicamba-5-aminopentanoic acid (DCc) is an immunizing and heterologous hapten, designed using the carboxylic acid group of dicamba to introduce a spacer arm for a better exposure of the herbicide's structure.
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- Formula: C9H13N5O2S
- Molecular Weight: 255.30
Cyromazine-3-mercaptopropanoic acid (Compound 7) is a hapten conjugated to BSA and OVA for immunoassays of triazine herbicides.
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- Formula: C9H13N5O4S2
- Molecular Weight: 319.36
Clothianidin-2-S-propanoic acid is a clothianidin hapten. Clothianidin-2-S-propanoic can be used for the research of insecticide.
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- Formula: C17H21N3O6
- Molecular Weight: 363.37
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- Formula: C16H19N3O5
- Molecular Weight: 333.34
AMOZ-CHPh-3-acid is hapten against furaltadone metabolite AMOZ. AMOZ-CHPh-3-acid can couple to BSA for immunogens and couple to OVA for coating antigen.
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- Formula: C10H15N3O5
- Molecular Weight: 257.24
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- Formula: C32H53NO9
- Molecular Weight: 595.76
Ursodeoxycholic acid 7-N-acetylglucosaminide is an immunizing and heterologous hapten.
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- Formula: C18H20N4O6
- Molecular Weight: 388.37
Trimethoprim fumaric acid (Compound CDI) is a universal hapten for ASGs (Antibacterial synergists) and can be used to design broadly specific monoclonal antibodies (mAbs) against ASGs. The mAb developed by Trimethoprim fumaric acid can be applied in ELISA to detect the residues of ASGs in foods of animal origin.
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