Kcna3 - potassium voltage-gated channel subfamily A member 3 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29731

Summary

Enables delayed rectifier Potassium Channel activity and outward rectifier Potassium Channel activity. Involved in potassium ion transmembrane transport. Located in membrane raft and plasma membrane. Is integral component of plasma membrane. Is active in calyx of Held and glutamatergic synapse. Is integral component of postsynaptic membrane and integral component of presynaptic membrane. Orthologous to human KCNA3 (potassium voltage-gated channel subfamily A member 3). [provided by Alliance of Genome Resources, Apr 2022]

Kcna3 Products (1)

mRNA Protein Name
NM_019270.4 NP_062143.3 potassium voltage-gated channel subfamily A member 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables delayed rectifier potassium channel activity IMP
IMP: Inferred from mutant phenotype
14602579 RGD
enables outward rectifier potassium channel activity IMP
IMP: Inferred from mutant phenotype
14602579 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
7477295 RGD
enables voltage-gated potassium channel activity IDA
IDA: Inferred from direct assay
2361015 RGD
enables voltage-gated potassium channel activity IMP
IMP: Inferred from mutant phenotype
2555158 RGD
Biological Process GO Annotation Evidence References Source
involved in corpus callosum development IEP
IEP: Inferred from expression pattern
22473424 RGD
involved in optic nerve development IEP
IEP: Inferred from expression pattern
22473424 RGD
involved in potassium ion transmembrane transport IMP
IMP: Inferred from mutant phenotype
2555158 RGD
Cellular Component GO Annotation Evidence References Source
is active in calyx of Held IDA
IDA: Inferred from direct assay
14614103 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
14614103 RGD
located in membrane raft IDA
IDA: Inferred from direct assay
18218624 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
18218624 RGD
located in plasma membrane IMP
IMP: Inferred from mutant phenotype
2555158 RGD
is active in postsynaptic membrane IDA
IDA: Inferred from direct assay
14614103 RGD
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
14614103 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

potassium voltage-gated channel subfamily A member 3

  • KV3

  • RCK3

  • RGK5

  • potassium channel, voltage gated shaker related subfamily A, member 3

  • potassium voltage-gated channel, shaker-related subfamily, member 3

  • voltage-gated potassium channel subunit Kv1.3

  • voltage-gated potassium channel subunit Kv3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07099 KCNA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22584 Kcna3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29101 Kcna3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcna3 NCBI NCBI:3738