EVA1A - eva-1 homolog A, regulator of programmed cell death Gene

Also Known as FAM176A; TMEM166

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84141

About EVA1A

Cytogenetic location: 2p12 Genomic coordinates (GRCh38): 2:75,492,318-75,569,719 (from NCBI)

This gene has 11 transcripts (splice variants), 263 orthologues and 1 paralogue. Biased expression in liver (RPKM 20.6), lung (RPKM 8.7) and 7 other tissues.

Summary

Predicted to be involved in apoptotic process and Autophagy. Located in intracellular membrane-bounded organelle and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

EVA1A Products (4)

mRNA Protein Name
NM_001135032.2 NP_001128504.1 protein eva-1 homolog A
NM_001369524.1 NP_001356453.1 protein eva-1 homolog A
NM_001369525.1 NP_001356454.1 protein eva-1 homolog A
NM_032181.3 NP_115557.1 protein eva-1 homolog A

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

EVA1A Protein Structure

FAM176

FAM176: FAM176 family (13 - 152)

  • 0
  • 100
  • 152 a.a.
Protein Preferred Names Protein Names

protein eva-1 homolog A

  • family with sequence similarity 176, member A

EVA1A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
EVA1A Q9H8M9 SGTB Homo sapiens Q96EQ0
Y2H Prey Pooling
32296183
Intra
EVA1A Q9H8M9 SGTB Homo sapiens Q96EQ0
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Fuchs' Endothelial Dystrophy

  • Fuchs Endothelial Corneal Dystrophy

  • Fuchs Endothelial Dystrophy

  • Fuchs Dystrophy

  • Fced

  • Fuchs' Corneal Dystrophy

  • Fuchs' Endothelial Corneal Dystrophy

  • Fuchs Atrophy

  • Fuchs Corneal Dystrophy

  • Endoepithelial Corneal Dystrophy

  • Fecd

  • Late Hereditary Endothelial Dystrophy

  • Corneal Dystrophy, Fuchs Endothelial

  • Dystrophy, Corneal, Fuchs Endothelial

  • Corneal Dystrophy, Fuchs' Endothelial, 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04571 EVA1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22496 Eva1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta EVA1A VGNC VGNC:106159
Mus musculus EVA1A MGD MGI:2385247
Canis familiaris EVA1A VGNC VGNC:54943
Rattus norvegicus EVA1A RGD RGD:1559797
Others EVA1A NCBI