Cys-HAP-1
Cys-HAP-1 is a synovium-homing peptide that specifically binds to human and rabbit fibroblast-like synoviocytes, and does not bind to human umbilical vein endothelial cells regardless of TNF-α treatment. Cys-HAP-1 enables targeted drug delivery to inflamed joints after conjugation with liposomes loaded with anti-arthritic agents. Cys-HAP-1 can be used in studies related to adjuvant arthritis.
For research use only. We do not sell to patients.
- Formula: C63H95N19O18S
- Molecular Weight:1438.61
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 1438.61
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Formula C63H95N19O18S
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Sequence
Cys-Ser-Phe-His-Gln-Phe-Ala-Arg-Ala-Thr-Leu-Ala-Ser
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Sequence Shortening
CSFHQFARATLAS
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Cys-HAP-1
- Others
- synovium
- anti-arthritic agents
- rabbit fibroblast-like synoviocytes (rFLS)
- fibroblast-like synoviocytes
- TNF-α
- human fibroblast-like synoviocytes (hFLS)
- inflamed joints
- rat adjuvant-induced arthritis model
- adjuvant-induced arthritis
- human umbilical vein endothelial cells
- Inhibitor
- inhibitor
- inhibit