Pyrazolam
Pyrazolam is a brominated triazolo benzodiazepine psychoactive substance with oral effectiveness. Pyrazolam produces anxiolytic, sedative, and sleep-promoting effects. Pyrazolam can be used for the research of anxiety.
For research use only. We do not sell to patients.
- CAS No.: 39243-02-2
- Formula: C16H12BrN5
- Molecular Weight:354.20
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Pyrazolam exerts a central inhibitory effect by binding to a specific allosteric regulatory site of the GABAA receptor to enhance the inhibitory effect of GABA, which increases the opening frequency of chloride channels and causes neuronal hyperpolarization[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 39243-02-2
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Molecular Weight 354.20
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Formula C16H12BrN5
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SMILES
BrC1=CC=C2C(C(C3=NC=CC=C3)=NCC4=NN=C(C)N24)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Manchester KR, et al. The blood-to-plasma ratio and predicted GABAA-binding affinity of designer benzodiazepines. Forensic Toxicol. 2022 Jul;40(2):349-356. [Content Brief]
[2]. Moosmann B, et al. Detection and identification of the designer benzodiazepine flubromazepam and preliminary data on its metabolism and pharmacokinetics. J Mass Spectrom. 2013;48(11):1150-1159. [Content Brief]
[3]. Mullin A, et al. Benzodiazepine Boom: Tracking Etizolam, Pyrazolam, and Flubromazepam from Pre-UK Psychoactive Act 2016 to Present Using Analytical and Social Listening Techniques. Pharmacy (Basel). 2024;12(1):13. Published 2024 Jan 12. [Content Brief]
[4]. Abouchedid R, et al. Assessment of the Availability, Cost, and Motivations for Use over Time of the New Psychoactive Substances-Benzodiazepines Diclazepam, Flubromazepam, and Pyrazolam-in the UK. J Med Toxicol. 2018;14(2):134-143. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pyrazolam Related Classifications
HY-W028389 Related Classifications
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