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United States

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製品番号: HY-115725

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Antileishmanial agent-1

Antileishmanial agent-1 exhibits the activity against L. amazonensis promastigotes (IC₅₀ = 15.52 μM) and intracellular amastigotes (IC₅₀ = 4.10 μM).

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CAS 番号: 2454115-43-4
分子式: C₁₅H₁₁Br₂N₃O
分子量:409.08

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Antileishmanial agent-1 構造式

CAS 番号: 2454115-43-4

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Antileishmanial agent-1 exhibits the activity against L. amazonensis promastigotes (IC₅₀ = 15.52 μM) and intracellular amastigotes (IC₅₀ = 4.10 μM).

Parasite アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
Peritoneal macrophage	CC₅₀	84.01 μM Compound: 4	Cytotoxicity against BALB/c mouse peritoneal macrophages assessed as reduction in cell viability incubated for 24 hrs by MTT assay Cytotoxicity against BALB/c mouse peritoneal macrophages assessed as reduction in cell viability incubated for 24 hrs by MTT assay	[PMID: 34427442]

化学情報

CAS 番号 2454115-43-4
分子量 409.08
分子式 C₁₅H₁₁Br₂N₃O
SMILES

OC(C1=CC=C(Br)C=C1)C2=CN(C3=CC=C(Br)C=C3)N=N2
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (267 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Almeida-Souza F, et al. Nitric Oxide Induction in Peritoneal Macrophages by a 1,2,3-Triazole Derivative Improves Its Efficacy upon Leishmania amazonensisIn Vitro Infection. J Med Chem. 2021 Sep 9;64(17):12691-12704. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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