Antitumor agent-71
Antitumor Agent-71 is an antiproliferative activity antitumor agent and against tumor cell lines with IC50 values ranging from 3.98-15.70 μM. Antitumor Agent-71 is an antitumor agent that can inhibit tubulin polymerization.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2011756-99-1
- 分子式: C26H31N5O4S
- 分子量:509.62
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
IC50 & Target
3.98/15.70/10.48/5.38 μM
体外実験
Antitumor agent-71 (0.002-20 μM; 48 hours) inhibits the cell line HepG2, MCF-7, MIA PaCa-2, and Bel-7402 growth in a dose-dependent manner[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HepG2, MCF-7, MIA PaCa-2, and Bel-7402[1].
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Concentration:0.002-20 μM
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Incubation Time:48h
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Result:Showed antitumor activity against HepG2, MIA PaCa-2, MCF-7, and Bel-7402 cell lines with the IC50 values of 3.98/15.70/10.48/5.38 μM.
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:HepG2 model BALB/c nude mice[1]
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Dosage:10mg/kg, 20mg/kg
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Administration:Intravenous injection; twice a day; 20 days
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Result:Inhibited tumor growth in a dose-dependent manner.
化学情報
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CAS 番号 2011756-99-1
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分子量 509.62
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分子式 C26H31N5O4S
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SMILES
O=S(C1=CC2=C(C=C1)N(C)C3=C2C=C(CN4CCN(C)CC4)C=C3)(NC5=CC=C(OC)N=C5OC)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Antitumor agent-71 関連分類
HY-146250 関連分類
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