Ap5dT
Ap5dT is a cytosolic thymidine kinase and mitochondrial enzyme inhibitor with Kis of 0.12 μM and 0.50 μM, respectively. Ap5dT can be used for the study of acute myelocytic leukemia.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 103137-88-8
- 分子式: C20H30N7O23P5
- 分子量:891.35
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| L1210 | IC50 |
14 μM
Compound: Ap5T
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Concentration required to reduce Ribonucleotide reductase rate by 50% in L1210 cells
Concentration required to reduce Ribonucleotide reductase rate by 50% in L1210 cells
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[PMID: 2838631] |
| L1210 | IC50 |
2.5 μM
Compound: Ap5T
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Concentration required to reduce thymidine kinase rate by 50% in L1210 cells
Concentration required to reduce thymidine kinase rate by 50% in L1210 cells
|
[PMID: 2838631] |
化学情報
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CAS 番号 103137-88-8
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分子量 891.35
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分子式 C20H30N7O23P5
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SMILES
O[C@@H]1[C@H](O)[C@@H](COP(OP(OP(OP(OP(OC[C@@H](O2)[C@@H](O)C[C@@H]2N3C(NC(C(C)=C3)=O)=O)(O)=O)(O)=O)(O)=O)(O)=O)(O)=O)O[C@H]1N4C5=NC=NC(N)=C5N=C4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Ap5dT 関連分類
HY-177023 関連分類
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