Baclofen (Standard)
Baclofen (Standard) is the analytical standard of Baclofen. This product is intended for research and analytical applications. Baclofen, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABAB receptor (GABABR) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98%
- CAS 番号: 1134-47-0
- 分子式: C10H12ClNO2
- 分子量:213.66
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
化学情報
- 純度とドキュメンテーション
-
Help & FAQs
-
HY-B0007
BaclofenGABABR Agonist -
HY-B1715
OxiracetamNootropic Agent -
HY-108403
PhenibutGABAB Agonist -
HY-B0009
FlumazenilGABA Receptor Antagonist -
HY-103531
CGP52432GABAB Antagonist -
HY-107994
Aminooxyacetic acid hemihydrochlorideGABA Receptor Inhibitor -
HY-A0057
GabapentinCalcium Channel Blocker. -
HY-17354
(R)-BaclofenGABA Receptor Agonist -
HY-13315
Montelukast sodiumCysltr1 Antagonist -
HY-B1833
AfloqualoneMuscle Relaxant Agent -
HY-13062
Daunorubicin hydrochlorideTopoisomerase II Inhibitor -
HY-100991
FG 7142GABAA Receptor Inhibitor
Product Information
説明
アプリケーション
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
化学情報
-
CAS 番号 1134-47-0
-
分子量 213.66
-
分子式 C10H12ClNO2
-
SMILES
O=C(O)CC(C1=CC=C(Cl)C=C1)CN
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
-
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
取扱説明書 (2659 KB)
参考文献
[1]. Mehdi Farokhnia, et al. A deeper insight into how GABA-B receptor agonism via baclofen may affect alcohol seeking and consumption: lessons learned from a human laboratory investigation. Mol Psychiatry. 2018 Oct 31. [Content Brief]
[2]. Bexis, S., et al., Baclofen prevents MDMA-induced rise in core body temperature in rats. Drug Alcohol Depend, 2004. 74(1): p. 89-96. [Content Brief]
[3]. Woori Kim, et al. Baclofen, a GABAB receptor agonist, enhances ubiquitin-proteasome system functioning and neuronal survival in Huntington's disease model mice. Biochem Biophys Res Commun. 2014 Jan 10;443(2):706-11. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Baclofen (Standard) 関連分類
HY-B0007R 関連分類
Powered by Bioz