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製品番号: HY-N18086

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Bruceanic acid D

Bruceanic acid D is a quassinoid compound and cytotoxic agent that can be isolated from the xylem powder of Brucea antidysenterica. Bruceanic acid D specifically inhibits P-388 lymphocytic leukemia cells but shows no activity against human lung cancer cells and human colon cancer cells. Bruceanic acid D can be used in studies related to P-388 lymphocytic leukemia.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 132587-61-2
分子式: C₂₇H₃₆O₁₃
分子量:568.57

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Bruceanic acid D 構造式

CAS 番号: 132587-61-2

容量

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

Bruceanic acid D (compound 5) exhibits cytotoxic activity against P-388 murine leukemia cells with an ED₅₀ of 0.77 μg/mL, and does not show cytotoxicity against A-549 or HCT-8 cells at the tested threshold^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 132587-61-2
分子量 568.57
分子式 C₂₇H₃₆O₁₃
SMILES

COC([C@]12[C@@]3([H])[C@@]4(CO2)[C@]([C@H]([C@@H]1O)O)([H])[C@](C)([C@@H](C[C@@]4([H])OC([C@@H]3OC(/C=C(C)/C(C)(O)C)=O)=O)C(C)=O)CC(O)=O)=O
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Microorganisms
Brucea antidysenterica
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (272 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Toyota T, et al. Antitumor agents, 118. The isolation and characterization of bruceanic acid A, its methyl ester, and the new bruceanic acids B, C, and D, from Brucea antidysenterica[J]. Journal of natural products, 1990, 53(6): 1526-1532.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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分子量分子量

希釈計算機

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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