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製品番号: HY-15386

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Cimoxatone

(別名: MD 780515)

Cimoxatone (MD 780515) is a reversible, selectively and orally active type A monoamine oxidase (MAO-A) inhibitor. Cimoxatone enhances the anorectic action of Serotonin (HY-B1473A).

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 73815-11-9
分子式: C₁₉H₁₈N₂O₄
分子量:338.36

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (241 KB)

Cimoxatone 構造式

CAS 番号: 73815-11-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cimoxatone (MD 780515) is a reversible, selectively and orally active type A monoamine oxidase (MAO-A) inhibitor. Cimoxatone enhances the anorectic action of Serotonin (HY-B1473A)^[1].

IC₅₀ & Target^[1]

MAO-A

Monoamine Oxidase アイソフォーム固有の製品をすべて表示 :

MAO-A
MAO-B

体内実験

Cimoxatone (20 mg/kg; p.o.) enhances the anorectic action of 5-HT (1 mg/kg; s.c.) in rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

250-300 g, Adult male Wistar rats^[1]
Dosage:

20 mg/kg
Administration:

P.o.
Result:

Significiantly reduced sucrose intake induced by 1 mg/kg 5-HT or its vehicle injected 2 and 24 h later, significantly enhanced the anorectic action of 5-HT at 2 h but not at 24 h.

化学情報

CAS 番号 73815-11-9
分子量 338.36
分子式 C₁₉H₁₈N₂O₄
SMILES

N#CC1=CC=CC(COC2=CC=C(N3C(OC(COC)C3)=O)C=C2)=C1
別名

MD 780515
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.