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製品番号: HY-P992530

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CM355

Name: CM355
Brand: MedChemExpress
SKU: HY-P992530
Availability: PreOrder

(別名: ICP-B02)

CM355 (ICP-B02) is a CD20/CD3 bispecific IgG4 antibody. CM355 exhibits asymmetric affinity binding to CD20 and CD3. CM355 does not bind to Fcγ receptors (FcγR), which is designed to reduce the risk of cytokine release. CM355 can be used for research on B-cell non-Hodgkin lymphoma.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

CM355 構造式

容量

価格（税別）

在庫状況

数量

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Top Publications Citing

Use of MCE Products

Antibody-Drug Conjugates

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

生物活性
- 製品説明
- Species Reactivity
- 体外実験
- Target
- Conjugated
- アプリケーション
化学情報
純度とドキュメンテーション
参考文献
Calculators
Help & FAQs
関連分類
Bioz

生物活性

製品説明

Species Reactivity

Human

体外実験

Adaptive Immunity

CM355 eliminates malignant B cells by inducing T cell-dependent cytotoxicity^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Research Protocol for Inflammation-related Diseases

Target

CD3 & CD20

Conjugated

Unconjugated

アプリケーション

ELISA, FACS, Functional assay

化学情報

SMILES

[CM355]
別名

ICP-B02
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

Inhibitory Antibodies User Guide (603 KB)

参考文献

[1]. SUBCUTANEOUS CM355, A NOVEL BISPECIFIC CD20/CD3 ANTIBODY
SHOWED PROMISING EFFICACY AND FAVORABLE SAFETY PROFILE IN
RELAPSED/REFRACTORY B-CELL NON-HODGKIN LYMPHOMA. EHA Library.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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