EU101
EU101 (NOV1801) is a humanized agonistic monoclonal antibody targeting the costimulatory receptor CD137, with potential immunostimulatory and antineoplastic activities.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
Species Reactivity
Human
体外実験
EU101 can target and bind to CD137 expressed on various leukocyte subsets, enhance CD137-mediated signaling, induce the proliferation of cytotoxic T lymphocytes and cytokine production, and promote cytotoxic T lymphocyte-mediated anti-tumor immune responses. Meanwhile, it can also induce natural killer cell-mediated tumor cell killing and suppress the immunosuppressive activity of regulatory T cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
臨床実験
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | 2011-05 | PHASE1 |
遺伝子ID
アクセッション番号
Target
TNFRSF9/4-1BB/CD137
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
アプリケーション
ELISA, FACS, Functional assay
化学情報
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SMILES
[EU101]
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別名
NOV1801
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. EU101.
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
EU101 関連分類
HY-P992044 関連分類
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