FPPS-IN-2
FPPS-IN-2 (compound 4a) is a potent and orally active HFPPS inhibitor with an IC50 value of 1.108 µM. FPPS-IN-2 has the potential for the research of osteoporosis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C24H26O6
- 分子量:410.46
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
IC50: 1.108 µM (HFPPS)[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:200-250 g, Female Wistar rats[1]
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Dosage:0.1, 1, 10 mg/kg
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Administration:P.o.; daily for 8 weeks
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Result:Increased the osteocalcin level only with the 1, and 10 mg/kg doses, reduced urinary calcium.
化学情報
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分子量 410.46
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分子式 C24H26O6
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SMILES
COC1=CC(/C=C/C(C)=O)=CC=C1OCCOC2=CC=C(/C=C/C(C)=O)C=C2OC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)