CKAP4 - cytoskeleton associated protein 4 Gene

Also Known as p63; CLIMP63; CLIMP-63; ERGIC-63

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 10970

About CKAP4

Cytogenetic location: 12q23.3 Genomic coordinates (GRCh38): 12:106,237,881-106,248,020 (from NCBI)

This gene has 3 transcripts (splice variants), 192 orthologues and 7 paralogues. Ubiquitous expression in bone marrow (RPKM 41.9), placenta (RPKM 30.9) and 25 other tissues.

Summary

Enables RNA binding activity. Located in several cellular components, including lipid droplet; nuclear speck; and rough endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

CKAP4 Products (1)

mRNA Protein Name
NM_006825.4 NP_006816.2 cytoskeleton-associated protein 4

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
19401338 GOA
located in lipid droplet IDA
IDA: Inferred from direct assay
14741744 GOA
located in rough endoplasmic reticulum IDA
IDA: Inferred from direct assay
24454821 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytoskeleton-associated protein 4

  • 63 kDa membrane protein

Recombinant CKAP4 Proteins

製品番号 製品名 アクセッション番号 純度
HY-P700976 CKAP4 Protein, Human (His) Q07065 (H128-V602) ≥ 90%, as determined by reducing SDS-PAGE.

CKAP4 抗体

製品番号 製品名 アプリケーション 反応性
HY-P810724 CKAP4 Antibody (YA9968) WB, ICC/IF, FC Human
HY-P84944 CKAP4 Antibody WB Human, Mouse

関連疾患

Diseases Alias
Cystitis

  • Infective Cystitis

  • Urocystitis

  • Pyocystitis
Bladder Exstrophy

  • Exstrophy Of The Bladder

  • Classic Exstrophy Of The Bladder
Axenfeld-Rieger Syndrome, Type 1

  • Axenfeld-Rieger Syndrome Type 1

  • RIEG1

  • Rieg

  • Rgs

  • Rieger Syndrome Type 1

  • Rieger Syndrome, Type 1

  • Axenfeld-Rieger Syndrome 1

  • Iridogoniodysgenesis With Somatic Anomalies
Retinitis Pigmentosa 20

  • RP20

  • Retinitis Pigmentosa, Type 20
Spastic Paraplegia 36, Autosomal Dominant

  • SPG36

  • Hereditary Spastic Paraplegia 36

  • Autosomal Dominant Spastic Paraplegia Type 36

  • Autosomal Dominant Spastic Paraplegia 36
Interstitial Cystitis

  • Bladder Pain Syndrome

  • Painful Bladder Syndrome

  • Ulcerative Cystitis

  • Ic/Bps

  • Ic/Pbs

  • Interstitial Cystitis/Bladder Pain Syndrome

  • Interstitial Cystitis/Painful Bladder Syndrome

  • Cystitis, Interstitial

  • Chronic Interstitial Cystitis

  • Pelvic Congestion Syndrome

  • Trigonitis
Amelogenesis Imperfecta

  • Ai

  • Congenital Enamel Hypoplasia

  • Al - [Amelogenesis Imperfecta]
Hereditary Spastic Paraplegia

  • Familial Spastic Paraplegia

  • Hereditary Spastic Paraparesis

  • Strumpell-Lorrain Disease

  • Familial Spastic Paraparesis

  • Hsp

  • Spg

  • Strümpell-Lorrain Disease

  • Spastic Paraplegia, Hereditary

  • French Settlement Disease

  • Strumpell-Lorrain Syndrome

  • Fsp

  • Spastic Paraplegia, Familial

  • Spastic Paraplegia Hereditary

  • Spastic Paraplegia 3, Autosomal Dominant

  • Spastic Paraparesis

  • Hereditary Spastic Paralysis

  • Familial Spastic Paralysis

  • Hereditary Spastic Ataxia
Cone-Rod Dystrophy 2

  • Cone-Rod Dystrophy

  • CORD2

  • Cone-Rod Retinal Dystrophy

  • Rcrd2

  • Cone-Rod Retinal Dystrophy 2

  • Crd2

  • Cord

  • Crd

  • Retinal Cone-Rod Dystrophy

  • Cone-Rod Retinal Dystrophy-2

  • Retinal Cone-Rod Dystrophy 2

  • Tapetoretinal Degeneration

  • Cone-Rod Degeneration

  • Cone Rod Dystrophy

  • Dystrophy, Cone-Rod

  • Dystrophy, Cone-Rod, Type 2

  • Retinitis Pigmentosa

  • Retinitis Pigmentosa 2

  • Progressive Cone-Rod Dystrophy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-178193A (Rac)-Chem-0199 Inhibitor 99.81% Unkown
HY-178193 Chem-0199 Inhibitor / Unkown
HY-RS02734 CKAP4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19421 Ckap4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25912 Ckap4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Canis familiaris CKAP4 VGNC VGNC:39288
Felis catus CKAP4 VGNC VGNC:83533
Mus musculus CKAP4 MGD MGI:2444926
Bos taurus CKAP4 VGNC VGNC:27382
Rattus norvegicus CKAP4 RGD RGD:1311989
Macaca mulatta CKAP4 VGNC VGNC:71190
Others CKAP4 NCBI