B3GNT6 - UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 Gene

Also Known as BGnT-6; B3Gn-T6; beta3Gn-T6; beta-1,3-Gn-T6

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 192134

About B3GNT6

Cytogenetic location: 11q13.5 Genomic coordinates (GRCh38): 11:77,034,398-77,041,973 (from NCBI)

This gene has 2 transcripts (splice variants), 803 orthologues and 15 paralogues. Biased expression in colon (RPKM 17.5), stomach (RPKM 11.9) and 4 other tissues.

Summary

The protein encoded by this gene is a beta-1,3-N-acetylglucosaminyltransferase that adds an N-acetylglucosamine moiety to N-acetylgalactosamine-modified serine or threonine. The encoded enzyme is responsible for creating the core 3 structure of O-glycans, which are important components of mucin-type glycoproteins. [provided by RefSeq, Dec 2016]

B3GNT6 Products (1)

mRNA Protein Name
NM_138706.5 NP_619651.3 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence 参考文献 由来
enables galactosyltransferase activity IDA
IDA: Inferred from direct assay
11821425 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase

  • beta-1,3-N-acetylglucosaminyltransferase 6

Recombinant B3GNT6 Proteins

製品番号 製品名 アクセッション番号 純度
HY-P76741 B3GNT6 Protein, Human (sf9, His) Q6ZMB0-1 (Q44-S384) ≥ 90%, as determined by reducing SDS-PAGE.

関連疾患

Diseases Alias
Childhood-Onset Schizophrenia

  • Childhood Schizophrenia

  • Schizophrenia, Childhood
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS01313 B3GNT6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01326 B4GAT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20527 B3gnt6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27036 B3gnt6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Macaca mulatta B3GNT6 VGNC VGNC:70123
Bos taurus B3GNT6 VGNC VGNC:26382
Felis catus B3GNT6 VGNC VGNC:60058
Rattus norvegicus B3GNT6 RGD RGD:1310926
Canis familiaris B3GNT6 VGNC VGNC:49799
Mus musculus B3GNT6 MGD MGI:3039603
Others B3GNT6 NCBI