GDPD1 - glycerophosphodiester phosphodiesterase domain containing 1 Gene

Also Known as GDE4

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 284161

About GDPD1

Cytogenetic location: 17q22 Genomic coordinates (GRCh38): 17:59,220,511-59,275,970 (from NCBI)

This gene has 7 transcripts (splice variants), 198 orthologues and 5 paralogues. Broad expression in brain (RPKM 4.9), testis (RPKM 3.0) and 22 other tissues.

Summary

This gene encodes a member of the glycerophosphodiester phosphodiesterase family of Enzymes that catalyze the hydrolysis of deacylated glycerophospholipids to glycerol phosphate and alcohol. The encoded protein is localized to the cytoplasm and concentrates near the perinuclear region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

GDPD1 Products (3)

mRNA Protein Name
NM_001165993.2 NP_001159465.1 lysophospholipase D GDPD1 isoform 3
NM_001165994.2 NP_001159466.1 lysophospholipase D GDPD1 isoform 2
NM_182569.4 NP_872375.2 lysophospholipase D GDPD1 isoform 1

GDPD1 Protein Structure

GDPD

GDPD: Glycerophosphoryl diester phosphodiesterase family (45 - 176)

  • 0
  • 100
  • 200
  • 300
  • 314 a.a.
Protein Preferred Names Protein Names

lysophospholipase D GDPD1

  • glycerophosphodiester phosphodiesterase 4

関連疾患

Diseases Alias
Retinitis Pigmentosa 17

  • RP17

  • Retinitis Pigmentosa-17

  • Retinitis Pigmentosa, Type 17
Branchiooculofacial Syndrome

  • Branchio-Oculo-Facial Syndrome

  • BOFS

  • Bof Syndrome

  • Hemangiomatous Branchial Clefts-Lip Pseudocleft Syndrome

  • Lip Pseudocleft-Hemangiomatous Branchial Cyst Syndrome

  • Branchial Clefts With Characteristic Facies, Growth Retardation, Imperforate Nasolacrimal Duct, And Premature Aging

  • Branchial Clefts With Characteristic Facies Growth Retardation Imperforate Nasolacrimal Duct And Premature Aging

  • Bofs Syndrome

  • Lip Pseudocleft-Hemagiomatous Branchial Cyst Syndrome
Retinitis Pigmentosa

  • RP

  • Rod-Cone Dystrophy

  • Autosomal Recessive Retinitis Pigmentosa

  • Non-Syndromic Retinitis Pigmentosa

  • Pericentral Pigmentary Retinopathy

  • Pigmentary Retinopathy

  • Tapetoretinal Degeneration

  • Rcd

  • Retinitis Pigmentosa Autosomal Recessive

  • ARRP

  • Retinitis Pigmentosa, Autosomal Recessive

  • Retinitis Pigmentosa 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS05362 GDPD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21580 Gdpd1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28098 Gdpd1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Canis familiaris GDPD1 VGNC VGNC:49766
Felis catus GDPD1 VGNC VGNC:99062
Bos taurus GDPD1 VGNC VGNC:29310
Macaca mulatta GDPD1 VGNC VGNC:99154
Mus musculus GDPD1 MGD MGI:1913819
Rattus norvegicus GDPD1 RGD RGD:1311813
Others GDPD1 NCBI