Ung - uracil-DNA glycosylase Gene

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 304577

Summary

Enables uracil DNA N-glycosylase activity. Involved in base-excision repair and negative regulation of apoptotic process. Located in mitochondrion. Human ortholog(s) of this gene implicated in dysgammaglobulinemia and immunodeficiency with hyper IgM type 5. Orthologous to human UNG (uracil DNA glycosylase). [provided by Alliance of Genome Resources, Apr 2022]

Ung Products (1)

mRNA Protein Name
NM_001013124.1 NP_001013142.1 uracil-DNA glycosylase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence 参考文献 由来
enables uracil DNA N-glycosylase activity IDA
IDA: Inferred from direct assay
11292851 RGD
Biological Process GO Annotation Evidence 参考文献 由来
involved in base-excision repair IDA
IDA: Inferred from direct assay
12167490 RGD
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
15297456 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

uracil-DNA glycosylase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-E70217 Uracil DNA Glycosylase (UDG/UNG), heat-sensitive / Unkown
HY-RS15478 UNG Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-112333 SC-68376 Inhibitor / Unkown
HY-RS18026 Ung Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24499 Ung Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Ung NCBI NCBI:7374
Mus musculus Ung NCBI NCBI:22256
Macaca mulatta Ung NCBI NCBI:706816