TMEM214 - transmembrane protein 214 Gene

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 54867

About TMEM214

Cytogenetic location: 2p23.3 Genomic coordinates (GRCh38): 2:27,032,965-27,041,694 (from NCBI)

This gene has 13 transcripts (splice variants) and 200 orthologues. Ubiquitous expression in placenta (RPKM 25.1), thyroid (RPKM 23.8) and 25 other tissues.

Summary

Predicted to be involved in apoptotic process. Located in several cellular components, including Golgi apparatus; cytoplasmic microtubule; and endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

TMEM214 Products (2)

mRNA Protein Name
NM_001083590.2 NP_001077059.1 transmembrane protein 214 isoform 2
NM_017727.5 NP_060197.4 transmembrane protein 214 isoform 1

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence 参考文献 由来
located in cytoplasmic microtubule IDA
IDA: Inferred from direct assay
23264731 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM214 Protein Structure

TMEM214

TMEM214: TMEM214, C-terminal, caspase 4 activator (217 - 684)

  • 0
  • 200
  • 400
  • 600
  • 689 a.a.
Protein Preferred Names Protein Names

transmembrane protein 214

関連疾患

Diseases Alias
Myopathy, X-Linked, With Postural Muscle Atrophy

  • Emery-Dreifuss Muscular Dystrophy 6, X-Linked

  • XMPMA

  • X-Linked Myopathy With Postural Muscle Atrophy

  • X-Linked Emery-Dreifuss Muscular Dystrophy 6

  • EDMD6

  • Emd6
Emery-Dreifuss Muscular Dystrophy 7, Autosomal Dominant

  • EDMD7

  • Autosomal Dominant Emery-Dreifuss Muscular Dystrophy 7

  • Emery-Dreifuss Muscular Dystrophy 7, Ad

  • Emd7

  • Dystrophy, Muscular, Emery-Dreifuss, Type 7, Autosomal Dominant
Emery-Dreifuss Muscular Dystrophy 5, Autosomal Dominant

  • EDMD5

  • Autosomal Dominant Emery-Dreifuss Muscular Dystrophy 5

  • Emd5

  • Dystrophy, Muscular, Emery-Dreifuss, Type 5, Autosomal Dominant
Emery-Dreifuss Muscular Dystrophy 4, Autosomal Dominant

  • EDMD4

  • Emery-Dreifuss Muscular Dystrophy 4 With Variable Features

  • Autosomal Dominant Emery-Dreifuss Muscular Dystrophy 4

  • Emd4

  • Dystrophy, Muscular, Emery-Dreifuss, Type 4, Autosomal Dominant

  • Emery-Dreifuss Muscular Dystrophy 4
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS14698 TMEM214 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Bos taurus TMEM214 VGNC VGNC:36036
Rattus norvegicus TMEM214 RGD RGD:1311324
Macaca mulatta TMEM214 VGNC VGNC:103879
Canis familiaris TMEM214 VGNC VGNC:47532
Mus musculus TMEM214 MGD MGI:1916046
Felis catus TMEM214 VGNC VGNC:66311
Others TMEM214 NCBI