NREP - neuronal regeneration related protein Gene

Also Known as P311; PTZ17; SEZ17; D4S114; C5orf13; PRO1873

生物種: Homo sapiens

遺伝子タイプ: protein coding

遺伝子ID: 9315

About NREP

Cytogenetic location: 5q22.1 Genomic coordinates (GRCh38): 5:111,728,802-111,976,932 (from NCBI)

This gene has 23 transcripts (splice variants) and 89 orthologues. Ubiquitous expression in brain (RPKM 38.4), placenta (RPKM 35.3) and 24 other tissues.

Summary

Predicted to be involved in axon regeneration; regulation of neuron differentiation; and regulation of transforming growth factor beta receptor signaling pathway. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

NREP Products (11)

mRNA	Protein	Name
NM_001142474.2	NP_001135946.1	neuronal regeneration-related protein isoform b
NM_001142475.2	NP_001135947.1	neuronal regeneration-related protein isoform c
NM_001142476.1	NP_001135948.1	neuronal regeneration-related protein isoform a
NM_001142477.1	NP_001135949.1	neuronal regeneration-related protein isoform a
NM_001142478.2	NP_001135950.1	neuronal regeneration-related protein isoform a
NM_001142479.1	NP_001135951.1	neuronal regeneration-related protein isoform a
NM_001142480.1	NP_001135952.1	neuronal regeneration-related protein isoform a
NM_001142481.1	NP_001135953.1	neuronal regeneration-related protein isoform a
NM_001142482.1	NP_001135954.1	neuronal regeneration-related protein isoform a
NM_001142483.1	NP_001135955.1	neuronal regeneration-related protein isoform a
NM_004772.4	NP_004763.1	neuronal regeneration-related protein isoform a

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	参考文献	由来
enables protein binding	IPI IPI: Inferred from physical interaction	22365962	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NREP Protein Structure

Alveol-reg_P311

0
68 a.a.

Protein Preferred Names	Protein Names
neuronal regeneration-related protein	neuronal protein 3.1

NREP Protein-protein interaction Information

Type	タンパク質名	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	参考文献
Intra	NREP	Q16612	EIF6	Homo sapiens	P56537	Confocal	22365962
Intra	NREP	Q16612	EIF6	Homo sapiens	P56537	IF	22365962
Intra	NREP	Q16612	EIF6	Homo sapiens	P56537	CoIP	22365962

Cross: Cross-species interaction Intra: Intraspecies interaction

Diseases	Alias
Febrile Seizures, Familial, 4	FEB4 Convulsions, Familial Febrile, 4 Familial Febrile Seizures 4 Familial Febrile Convulsions 4
Chronic Purulent Otitis Media	Chronic Suppurative Otitis Media Csom - [Chronic Suppurative Otitis Media]
Familial Febrile Seizures	Familial Febrile Convulsions Feb Febrile Seizures, Familial

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-RS09566	NREP Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21395	Nrep Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27914	Nrep Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

生物種	Symbol	由来	ID
Macaca mulatta	NREP	VGNC	VGNC:84454
Mus musculus	NREP	MGD	MGI:99444
Felis catus	NREP	VGNC	VGNC:102271
Canis familiaris	NREP	VGNC	VGNC:53193
Rattus norvegicus	NREP	RGD	RGD:631411
Others	NREP	NCBI