NREP - neuronal regeneration related protein Gene

Also Known as P311; PTZ17; SEZ17; D4S114; C5orf13; PRO1873

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9315

About NREP

Cytogenetic location: 5q22.1 Genomic coordinates (GRCh38): 5:111,728,802-111,976,932 (from NCBI)

This gene has 23 transcripts (splice variants) and 89 orthologues. Ubiquitous expression in brain (RPKM 38.4), placenta (RPKM 35.3) and 24 other tissues.

Summary

Predicted to be involved in axon regeneration; regulation of neuron differentiation; and regulation of transforming growth factor beta receptor signaling pathway. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

NREP Products (11)

mRNA Protein Name
NM_001142474.2 NP_001135946.1 neuronal regeneration-related protein isoform b
NM_001142475.2 NP_001135947.1 neuronal regeneration-related protein isoform c
NM_001142476.1 NP_001135948.1 neuronal regeneration-related protein isoform a
NM_001142477.1 NP_001135949.1 neuronal regeneration-related protein isoform a
NM_001142478.2 NP_001135950.1 neuronal regeneration-related protein isoform a
NM_001142479.1 NP_001135951.1 neuronal regeneration-related protein isoform a
NM_001142480.1 NP_001135952.1 neuronal regeneration-related protein isoform a
NM_001142481.1 NP_001135953.1 neuronal regeneration-related protein isoform a
NM_001142482.1 NP_001135954.1 neuronal regeneration-related protein isoform a
NM_001142483.1 NP_001135955.1 neuronal regeneration-related protein isoform a
NM_004772.4 NP_004763.1 neuronal regeneration-related protein isoform a

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22365962 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NREP Protein Structure

Alveol-reg_P311

Alveol-reg_P311: Neuronal protein 3.1 (p311) (1 - 68)

  • 0
  • 68 a.a.
Protein Preferred Names Protein Names

neuronal regeneration-related protein

  • neuronal protein 3.1

NREP Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
NREP Q16612 EIF6 Homo sapiens P56537
Confocal
22365962
Intra
NREP Q16612 EIF6 Homo sapiens P56537
IF
22365962
Intra
NREP Q16612 EIF6 Homo sapiens P56537
CoIP
22365962
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Febrile Seizures, Familial, 4

  • FEB4

  • Convulsions, Familial Febrile, 4

  • Familial Febrile Seizures 4

  • Familial Febrile Convulsions 4
Chronic Purulent Otitis Media

  • Chronic Suppurative Otitis Media

  • Csom - [Chronic Suppurative Otitis Media]
Familial Febrile Seizures

  • Familial Febrile Convulsions

  • Feb

  • Febrile Seizures, Familial
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09566 NREP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21395 Nrep Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27914 Nrep Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta NREP VGNC VGNC:84454
Mus musculus NREP MGD MGI:99444
Felis catus NREP VGNC VGNC:102271
Canis familiaris NREP VGNC VGNC:53193
Rattus norvegicus NREP RGD RGD:631411
Others NREP NCBI