KI 1769
KI 1769 is a potassium channel opener. KI 1769 can exhibit vasodilating effect. KI 1769 prolongs the micturition interval and reduces the resistance to fluid infusion through the urethral lumen. KI 1769 can be used for the research of cardiovascular disease.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 133300-00-2
- 分子式: C15H14N4
- 分子量:250.30
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体内実験
KI 1769 (0.3 mg/kg, i.v.) prolongs the micturition interval and reduces the resistance to fluid infusion through the urethral lumen in rats[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 133300-00-2
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分子量 250.30
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分子式 C15H14N4
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SMILES
N#CN/C(C1=CC=CN=C1)=N/CCC2=CC=CC=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Izumi H, et al. In vitro and in vivo vasodilating effects of KRN4884, Ki1769 and Ki3005, pyridinecarboxamidine derivatives. Fundam Clin Pharmacol. 1997;11(6):561-6. [Content Brief]
[2]. Kontani H, et al. Effect of K+ channel openers, KRN2391 and Ki1769, and nitroglycerin on the urinary tract of rats in vivo. Jpn J Pharmacol. 1999 Jun;80(2):143-53. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)