Lactonamycin
Lactonamycin had strong activity against Gram-positive bacteria including Staphylococcus, Streptococcus, Enterococcus, MRSA (MIC of 0.39-0.78 μg/mL) and VRE (MIC of 0.39-0.78 μg/mL). Lactonamycin also has inhibitory effect on L-1210, P388, S180, FS-3, Ehrlich, B16-BL5 and other tumor cell lines (IC50s of 0.06-3.3 μg/mL).
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 182234-02-2
- 分子式: C28H27NO12
- 分子量:569.51
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| EL4 | IC50 |
112 nM
Compound: 34
|
Cytotoxicity against mouse EL4 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Cytotoxicity against mouse EL4 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
|
[PMID: 38092421] |
| L1210 | IC50 |
153 nM
Compound: 34
|
Antiproliferative activity against mouse L1210 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against mouse L1210 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 38092421] |
化学情報
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CAS 番号 182234-02-2
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分子量 569.51
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分子式 C28H27NO12
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SMILES
CO[C@](OC1)(CC(O2)=O)[C@]2(C(C(C(C3=O)=CC4=C5)=C(O)C4=C6C(C(N(C6)C)=O)=C5O)=O)[C@@]13O[C@@H]7O[C@H]([C@H](CC7)O)C
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)