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United States

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製品番号: HY-155825

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LPE-1

LPE-1 is a lysine-specific demethylase 1 (LSD1) inhibitor with an IC₅₀ of 0.65 μM. LPE-1 inhibits the proliferation of gastric cancer, liver cancer and prostate cancer cells, and shows no activity against a subset of gastric cancer cells. LPE-1 is applicable for the research of gastric cancer, liver cancer and prostate cancer.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 1637373-70-6
分子式: C₁₃H₁₀N₆S₃
分子量:346.45

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

LPE-1 構造式

CAS 番号: 1637373-70-6

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

LPE-1 (Compound Ⅰ-12) (72 h) inhibits the proliferation of MGC-803 (IC₅₀ = 7.85 μM), HGC-27 (IC₅₀ = 5.16 μM), HepG2 (IC₅₀ = 5.71 μM) and PC-3 (IC₅₀ = 7.21 μM) cells, but shows no detectable activity against SGC-7901 cells (IC₅₀ >128 μM)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 1637373-70-6
分子量 346.45
分子式 C₁₃H₁₀N₆S₃
SMILES

N#CC=1C(=NC(=NC1C=2SC=CC2)SCC#C)NNC(=S)N
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Liu, et al. Pyrimidine derivatives containing semicarbazide and terminal alkyne structural units, and preparation methods and applications of pyrimidine derivatives. CN104119280 A.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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