Macrocarpal H
Based on 1 Customer Validation
Macrocarpal H is a natural compound that can be isolated from the Leaves of Eucalyptus globulus. Macrocarpal H exhibits antibacterial activity against Gram-positive cariogenic bacteria and Gram-negative periodontopathic bacteria. Macrocarpal H inhibits adherent water-insoluble glucan synthesis via glucosyltransferase. Macrocarpal H can be used for the research of caries, periodontal disease, dental caries, periodontal disorders.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 73.0%
- CAS 番号: 179388-53-5
- 分子式: C28H40O6
- 分子量:472.61
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保管条件:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
生物活性
Macrocarpal H (compound 7) (24-48 h) potently inhibits the growth of cariogenic bacteria including S. mutans Ingbritt, S. mutans LA7, S. sobrinus 6715, S. sobrinus B13, and A. viscosus 15987, and periodontopathic bacteria including P. gingivalis 33277, P. melaninogenica 25845, P. intermedia 25611, and C. ochracea 33596, with MIC values ranging from 0.39 to 3.13 µg/mL, and shows weaker activity against F. nucleatum 25586 with an MIC of 6.25 µg/mL[2].
Macrocarpal H (1-100 µg/mL; 16 h) strongly inhibits glucosyltransferase activity from S. sobrinus 6715, reducing adherent water-insoluble glucan synthesis by 97.6% at 100 µg/mL and 64.0% at 10 µg/mL[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 179388-53-5
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性状 Solid
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分子量 472.61
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分子式 C28H40O6
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Color Light yellow to yellow
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SMILES
CC(C)C[C@H](C1=C(C(C=O)=C(O)C(C=O)=C1O)O)[C@@]2([H])[C@]3([C@@](C(CC2)=C)([H])C[C@H](C(C)(O)C)CC3)C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
純度とドキュメンテーション
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データシート (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
- Macrocarpal H
- 179388-53-5
- Glucosylceramide Synthase (GCS)
- Bacterial
- periodontal disease
- Gram-negative periodontopathic bacteria
- Gram-positive cariogenic bacteria
- glucosyltransferase
- periodontopathic bacteria
- caries
- S. mutans Ingbritt
- periodontal disorders
- cariogenic bacteria
- dental caries
- Inhibitor
- inhibitor
- inhibit