NAIA
NAIA (N-Acryloylindole-alkyne) is a cysteine-reactive probe. NAIA can be used as an imaging agent, proteome profiling agent, and covalent ligand screening tool.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3020685-33-7
- 分子式: C19H20N2O3
- 分子量:324.37
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
NAIA enables proteome-wide identification of functional cysteines in HepG2 cell lysates via MS-based ABPP[2].
NAIA enables functional cysteine profiling in live cells and cancer cell lysates[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
化学情報
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CAS 番号 3020685-33-7
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分子量 324.37
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分子式 C19H20N2O3
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SMILES
O=C(N1C=CC2=C1C=CC(OCC(NCCCCC#C)=O)=C2)C=C
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別名
N-Acryloylindole-alkyne
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Koo TY, et al. N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. [Content Brief]
[2]. Koo TY, et al. Activity-Based Protein Profiling for Functional Cysteines and Protein Target Identification. Methods Mol Biol. 2025;2921:331-344. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
NAIA 関連分類
HY-183740 関連分類
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