Naphthohydroquinone
Based on 1 Customer Validation
Naphthohydroquinone is a compound featuring a naphthalene ring structure with two hydroxyl groups. Naphthohydroquinone exhibits significant cytotoxicity and antitumor activity in some of its derivatives.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 571-60-8
- 分子式: C10H8O2
- 分子量:160.17
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保管条件:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
10 μM
Compound: 29
|
Inhibition of human recombinant IDO expressed in HEK293 cells assessed as blockade of tryptophan degradation by HPLC
Inhibition of human recombinant IDO expressed in HEK293 cells assessed as blockade of tryptophan degradation by HPLC
|
[PMID: 20055453] |
| HFL1 | ED50 |
1 μM
Compound: 1a
|
Antiproliferative activity against human fibroblast HFL1 cells
Antiproliferative activity against human fibroblast HFL1 cells
|
[PMID: 16539380] |
| T-24 | ED50 |
0.7 μM
Compound: 1a
|
Antiproliferative activity against human bladder carcinoma T24 cells
Antiproliferative activity against human bladder carcinoma T24 cells
|
[PMID: 16539380] |
化学情報
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CAS 番号 571-60-8
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性状 Solid
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分子量 160.17
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分子式 C10H8O2
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SMILES
OC1=CC=C(O)C=2C=CC=CC12
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
溶剤 & 溶解度
体外:
DMSO : 50 mg/mL (312.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.2434 mL | 31.2168 mL | 62.4337 mL | 156.0842 mL |
| 5 mM | 1.2487 mL | 6.2434 mL | 12.4867 mL | 31.2168 mL | |
| 10 mM | 0.6243 mL | 3.1217 mL | 6.2434 mL | 15.6084 mL | |
| 15 mM | 0.4162 mL | 2.0811 mL | 4.1622 mL | 10.4056 mL | |
| 20 mM | 0.3122 mL | 1.5608 mL | 3.1217 mL | 7.8042 mL | |
| 25 mM | 0.2497 mL | 1.2487 mL | 2.4973 mL | 6.2434 mL | |
| 30 mM | 0.2081 mL | 1.0406 mL | 2.0811 mL | 5.2028 mL | |
| 40 mM | 0.1561 mL | 0.7804 mL | 1.5608 mL | 3.9021 mL | |
| 50 mM | 0.1249 mL | 0.6243 mL | 1.2487 mL | 3.1217 mL | |
| 60 mM | 0.1041 mL | 0.5203 mL | 1.0406 mL | 2.6014 mL | |
| 80 mM | 0.0780 mL | 0.3902 mL | 0.7804 mL | 1.9511 mL | |
| 100 mM | 0.0624 mL | 0.3122 mL | 0.6243 mL | 1.5608 mL |