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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
BQZ485
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "BQZ485" in MCE Product Catalog:
製品番号: HY-156242
CAS 番号: 1906915-49-8
研究分野:
BQZ-485 is a GDI2 inhibitor and a paraptosis inducer with antitumor activity. BQZ-485 binds to the Rab-binding platform domain of GDI2, disrupts the interaction between GDI2 and Rab1A, and impairs the membrane recycling of Rab1A. BQZ-485 blocks vesicle trafficking from the endoplasmic reticulum to the Golgi apparatus, and induces endoplasmic reticulum expansion, endoplasmic reticulum fusion, endoplasmic reticulum stress, unfolded protein response and cytoplasmic vacuolization. BQZ-485 is applicable to pancreatic cancer-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
