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製品番号: HY-122196

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TYT-1

TYT-1 is a sulfonamide-thiourea compound that has inhibitory activity against West Nile virus replication with a 50% effective concentration of 0.7 microM, blocking a post-entry, pre-assembly step of viral replication.

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CAS 番号: 64803-10-7
分子式: C₂₁H₁₇N₃O₂S₃
分子量:439.57

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

TYT-1 構造式

CAS 番号: 64803-10-7

容量

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
Vero	CC₅₀	>70 μM Compound: TYT-1	Cytotoxicity against african green monkey Vero cells after 48 hrs by MTS method Cytotoxicity against african green monkey Vero cells after 48 hrs by MTS method	[PMID: 17452483]
Vero	CC₅₀	>70 μM Compound: TYT-1	Cytotoxicity against african green monkey Vero cells by trypan blue exclusion assay Cytotoxicity against african green monkey Vero cells by trypan blue exclusion assay	[PMID: 17452483]
Vero	EC₅₀	0.7 μM Compound: TYT-1	Antiviral activity against West Nile virus NY 1999 infected in african green monkey Vero cells assessed as reduction of virus yield relative to control Antiviral activity against West Nile virus NY 1999 infected in african green monkey Vero cells assessed as reduction of virus yield relative to control	[PMID: 17452483]
Vero	EC₅₀	7 μM Compound: TYT-1	Antiviral activity against Japanese encephalitis virus SA14-2-8 infected in african green monkey Vero cells assessed as reduction of virus yield relative to control Antiviral activity against Japanese encephalitis virus SA14-2-8 infected in african green monkey Vero cells assessed as reduction of virus yield relative to control	[PMID: 17452483]

化学情報

CAS 番号 64803-10-7
分子量 439.57
分子式 C₂₁H₁₇N₃O₂S₃
SMILES

S=C(N(C1=CC=CC=C1)C2=CC=CC=C2)/N=C(N3C4=CC=CC=C4)\SCS3(=O)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (271 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Sultam thiourea inhibition of West Nile virus

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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