Ubiquinone-1
Based on 1 Customer Validation
Ubiquinone-1 is an intermediate in the synthesis of Coenzyme Q. Ubiquinone-1 can be reduced by NADPH oxidase, hepatoma cells, Ascorbic acid (HY-B0166).
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- Purity: 99.0%
- CAS No.: 727-81-1
- 화학식: C14H18O4
- 분자량:250.29
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보관:
Solution, -20°C, 2 years
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
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Human Endogenous Metabolite |
Ubiquinone-1 (60 µM) induces external deamino-NADH oxidation in potato tuber mitochondria by altering the specificity of an external Rotenone (HY-B1756)-insensitive NADH dehydrogenase[1].
Ubiquinone-1 (100 µM) is rapidly and efficiently reduced to extracellularly detectable ubiquinol-1 by whole blood, isolated erythrocytes, and human hepatoma HepG2 cells[3].
Ubiquinone-1 (150 µM) is reduced by NADPH oxidase of guinea pig macrophages under anaerobic conditions[4].
Ubiquinone-1 is reduced by Ascorbic acid (HY-B0166) in a molecular oxygen concentration-controlled process[5].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 727-81-1
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Appearance Liquid
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분자량 250.29
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화학식 C14H18O4
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Color Orange to red
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SMILES
O=C1C(OC)=C(OC)C(C(C)=C1C/C=C(C)\C)=O
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Structure Classification
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Solution, -20°C, 2 years
순도&문서
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Data Sheet (269 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Moller IM, et al. Ubiquinone-1 Induces External Deamino-NADH Oxidation in Potato Tuber Mitochondria. Plant Physiol. 1996 Sep;112(1):75-78. [Content Brief]
[2]. R Fato, et al. Steady-state kinetics of the reduction of coenzyme Q analogs by complex I (NADH:ubiquinone oxidoreductase) in bovine heart mitochondria and submitochondrial particles. Biochemistry. 1996 Feb 27;35(8):2705-16. [Content Brief]
[3]. Stocker R, et al. Extracellular reduction of ubiquinone-1 and -10 by human Hep G2 and blood cells. Biochim Biophys Acta. 1993 Aug 20;1158(1):15-22. [Content Brief]
[4]. Murakami M, et al. NADPH oxidase of guinea-pig macrophages catalyses the reduction of ubiquinone-1 under anaerobic conditions. Biochem J. 1986 Jul 15;237(2):541-5. [Content Brief]
[5]. Roginsky VA, et al. Reduction of ubiquinone-1 by ascorbic acid is a catalytic and reversible process controlled by the concentration of molecular oxygen. Redox Rep. 1996 Feb;2(1):55-62. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ubiquinone-1 Related Classifications
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