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Avocadyne

Avocadyne is an orally active mitochondrial fatty acid oxidation (FAO) inhibitor. Avocadyne induces leukemia cell death and reverses diet-induced obesity. Avocadyne inhibits fatty acid oxidation activity in leukemia cells. Avocadyne can be used in studies related to leukemia and obesity.

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CAS No.: 129099-93-0
화학식: C₁₇H₃₂O₃
분자량:284.44

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Avocadyne Chemical Structure

CAS No.: 129099-93-0

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Bioz

Biological Activity

제품 설명

Cellular Effect

Cell Line	Type	Value	Description	References
A498	IC₅₀	4.1 μg/mL Compound: 3	Cytotoxicity against human A498 cells by MTT assay Cytotoxicity against human A498 cells by MTT assay	[PMID: 9644064]
A549	IC₅₀	4.8 μg/mL Compound: 3	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 9644064]
HT-29	IC₅₀	8.9 μg/mL Compound: 3	Cytotoxicity against human HT-29 cells by MTT assay Cytotoxicity against human HT-29 cells by MTT assay	[PMID: 9644064]
MCF7	IC₅₀	6.5 μg/mL Compound: 3	Cytotoxicity against human MCF7 cells by MTT assay Cytotoxicity against human MCF7 cells by MTT assay	[PMID: 9644064]
MIA PaCa-2	IC₅₀	>10 μg/mL Compound: 3	Cytotoxicity against human MIAPaCa2 cells by MTT assay Cytotoxicity against human MIAPaCa2 cells by MTT assay	[PMID: 9644064]
PC-3	IC₅₀	0.61 ng/mL Compound: 3	Cytotoxicity against human PC3 cells by MTT assay Cytotoxicity against human PC3 cells by MTT assay	[PMID: 9644064]

In Vitro

Avocadyne (72 h) potently reduces the viability of TEX and AML2 leukemia cells, with IC₅₀ values of 3.10 μM and 11.53 μM, respectively^[2].
Avocadyne (10 μM; 7-14 days) potently inhibits the clonogenic capacity of AML cells^[2].
Avocadyne (10 μM; 3 h) inhibits fatty acid oxidation activity in TEX and AML2 leukemia cells^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 129099-93-0
분자량 284.44
화학식 C₁₇H₃₂O₃
SMILES

C(CCCCCCCCCCC#C)[C@H](C[C@H](CO)O)O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Ahmed N, et al.. Bioaccessibility of avocado polyhydroxylated fatty alcohols. Food chemistry. 2025 Jan 15;463(Pt 1):140811. [Content Brief]

[2]. Tcheng M, et al.. Avocado-derived avocadyne is a potent inhibitor of fatty acid oxidation. Journal of food biochemistry. 2022 Mar;46(3):e13895. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration Concentration

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Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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