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Cat. No.: HY-184054

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Balumorexton

Balumorexton is an orally active orexin type 2 receptor (OX2R) agonist. Balumorexton is used for the research of narcolepsy.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 3037907-48-2
화학식: C₂₀H₁₂F₆N₄O₄S
분자량:518.39

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Balumorexton Chemical Structure

CAS No.: 3037907-48-2

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
- In Vivo
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Balumorexton is an orally active orexin type 2 receptor (OX2R) agonist. Balumorexton is used for the research of narcolepsy^[1].

IC₅₀ & Target

^[1]

OX2R

All Orexin Receptor (OX Receptor) Isoforms :

In Vitro

Balumorexton (Example 77) (3 μM; calcium flux endpoint assay) exhibits OX2R agonistic activity in CHO-K1 cells stably expressing human OX2R, with a relative activation rate of 100%^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Balumorexton (Example 77) (1 mg/kg; p.o.; single administration) increases the wakefulness duration of cynomolgus monkeys, which reaches 645.09% of that in the vehicle control group^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3037907-48-2
분자량 518.39
화학식 C₂₀H₁₂F₆N₄O₄S
SMILES

FC1=CC=C2ON=C(N3C=C4N(C[C@H](C4(F)F)NS(C)(=O)=O)C3=O)C2=C1C5=C(C=C(C=C5F)F)F
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Hattori Y, et al. Heterocyclic compound. WO2024095133A1. WIPO; 2024 May 10.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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