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United States

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Cat. No.: HY-168707

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CK2-IN-14

CK2-IN-14 (Compound 10b) is an inhibitor for cyclin kinase 2α with an IC₅₀ of 36.7 nM. CK2-IN-14 inhibits the growth of cancer cell 786-O and U937 with GI₅₀ of 7.3 μM and 7.5 μM.

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화학식: C₁₉H₂₀ClN₅S
분자량:385.91

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

CK2-IN-14 Chemical Structure

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

CK2-IN-14 (Compound 10b) is an inhibitor for cyclin kinase 2α with an IC₅₀ of 36.7 nM. CK2-IN-14 inhibits the growth of cancer cell 786-O and U937 with GI₅₀ of 7.3 μM and 7.5 μM^[1].

IC₅₀ & Target

CK2

0.66 nM (IC₅₀)

All Casein Kinase Isoforms :

Chemical Information

분자량 385.91
화학식 C₁₉H₂₀ClN₅S
SMILES

ClC1=CC=C(C=C1)N2CCN(CC2)C3=NC=NC4=C3C5=C(S4)CNCC5
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Khalifa H, et al., Discovery of a novel, selective CK2 inhibitor class with an unusual basic scaffold. Eur J Med Chem. 2025 Jan 15;282:117048. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

견적 받기 해외재고보유

Other size

견적 받기

Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

CK2-IN-14

All Casein Kinase Isoforms

Biological Activity

제품 설명

IC50 & Target

Chemical Information

순도&문서

References

Calculators

Help & FAQs

CK2-IN-14 Related Classifications

HY-168707 Related Classifications

Bioz

Keywords

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IC₅₀ & Target